The Nu Difference
Complete layers set NuShield® apart
NuShield is a shelf-stable, dehydrated placental allograft wound covering that undergoes a unique preservation method.
- NuShield retains all layers of the placental membrane, including the spongy layer, for a more complete growth factor release1,2
- In vitro, growth factor proteins in NuShield continue to be released over a 7-day period2
The most complete dehydrated placental allograft wound covering
NuShield is an effective choice as a natural dehydrated placental allograft wound covering for a variety of partial- and full-thickness acute and chronic wounds, with a unique preservation method that retains1,3:
Numerous growth factors and cytokines with angiogenic, regenerative, and anti-inflammatory properties.2,4
All the native amnion and chorion layers with the spongy layer intact, unlike many placental allografts on the market2
Proven growth factor release
In vitro studies have shown that NuShield:
- Contains 640 proteins, including growth factors, cytokines, and chemokines4
- Releases growth factors and cytokines over a 7-day period to help create a favorable environment for healing2
- Increases fibroblast and keratinocyte proliferation and migration2
In vitro, the proprietary preservation method for NuShield retains numerous growth factors and cytokines. These growth factors and cytokines are known to have angiogenic, regenerative, and anti-inflammatory properties.*5
In vitro, NuShield continues to release growth factors over a 7-day period
An in vitro study demonstrated NuShield releases 32% of growth factors at 12 hours and 94% by 7 days.2
Total growth factor and cytokine release
- Data on file. Description of BioLoc Process.
- McQuilling JP, et al. Int Wound J. 2019;16(3):827-840.
- NuShield Allograft Tissue Information and Instructions for Use. Canton, MA: Organogenesis Inc; 2019.
- McQuilling JP, et al. Wound Repair Regen. 2019;27(6):609-621.
- McQuilling JP, et al. Wounds. 2017;29(6):E38-E42.